ea0022p202 | Clinical case reports and clinical practice | ECE2010
Galesanu Corina
, Florescu Alexandru
, Grozavu Ilinka
, Iovita Petronela
, Galesanu Mihail-Romeo
Introduction: Osteogenesis Imperfecta (O.I.) is a genetic disorder commonly known as brittle bone disease. The majority of people with O.I. have a mutation in one of two genes, COL 1A1 or COL 1A2, that encode type I collagen. In most families, O.I. is inherited in an autosomal dominant pattern. Dual Energy X-ray Absorptiometry - bone mineral density (DXA-BMD) test provides information about bone quantity, not quality. The bisphosphonates - treatment can minimizing fractures by...